HALLUCINATION AND IMAGERY INDUCED BY MESCALINE
Thomas Thale, Beverly W. Gabrio, Kurt Salomon
American Journal of Psychiatry March 1, 1950 DOI: 10.1176/ajp.106.9.686 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Experimental study Peer reviewed |
|---|---|
| Population | Subjects (patients) |
| Intervention | Mescaline |
| Topics | Mescaline |
| Keywords | Hallucinating Mental image Visual hallucination Optical illusion Hallucinogen Audiology Cognitive psychology Drug-induced ocular toxicity |
| Citations | 5 |
| Key findings | Mescaline reduces reported visual imagery in a dose-dependent manner, and this decline is not explained by the vividness of hallucinations or changes in actual vision. |
Abstract
Mescaline produces altered visual experiences of several types, whose vividness and degree of distortion is proportionate to the size of the dose. There are no sharp boundaries dividing abnormal sensibility, illusions, and hallucinations. Subjects who gave fewer responses of the type "I see it" when asked to imagine situations were more likely to hallucinate than other patients. Visual responses declined still further after administration of mescaline in a degree more closely related to the amount of drug given than to the vividness of hallucinatory alterations, even in those experimental subjects who reported virtually no alteration in actual vision. The fall in reported visual imagery was not found in control subjects.
Comparable studies
Other experimental studies on mescaline, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Enzymatic Formation of Psychotomimetic Metabolites from Normally Occurring Compounds Rabbit lung | 1961 | Experimental study | |
| PSYCHOTOMIMETICS, CLINICAL AND THEORETICAL CONSIDERATIONS: HARMINE, WIN-2299 AND NALLINE Schizophrenic patients | 1957 | Experimental study | |
| Phencyclidine, Lysergic Acid Diethylamide, and Mescaline: Cerebral Artery Spasms and Hallucinogenic Activity Isolated basilar and middle cerebral arteries | 1981 | Experimental study | |
| Acquired and Crossed Tolerance to Mescaline, LSD-25, and BOL-148 | 1959 | Experimental study | |
| Effects of Hallucinogenic and Tranquilizing Drugs on Serotonin Evoked Uterine Contractions. Uterus of spayed rat | 1956 | Experimental study |
Citations in the library
Cited by 2
Cites 3
- Artificial Psychoses Produced by Mescaline Journal of Mental Science May 1, 1936
- A Clinical Study of the Mescaline Psychosis, with Special Reference to the Mechanism of the Genesis of Schizophrenic and Other Psychotic States Journal of Mental Science 1940
- MESCALINE HALLUCINATIONS IN ARTISTS Archives of Neurology And Psychiatry 1941