Desipramine: A Possible Treatment for Depersonalization Disorder*
Russell Noyes, Samuel Kuperman, Stephen B. Olson
The Canadian Journal of Psychiatry December 1, 1987 DOI: 10.1177/070674378703200911 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A single patient with primary depersonalization disorder |
| Intervention | Desipramine |
| Key findings | The authors report successful treatment of one case of primary depersonalization disorder with desipramine, a condition they describe as generally resistant to treatment. They suggest that, given a proposed link between depersonalization and anxiety disorders, tricyclic antidepressants may prove effective for depersonalization. |
Abstract
Primary depersonalization disorder is believed to be resistant to treatment. However, we report the successful treatment of a case with desipramine and suggest that, because there is a link between depersonalization and anxiety disorders, tricyclic antidepressants may prove effective for depersonalization.