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Frontiers in Human Neuroscience

ISSN 1662-5161

315 papers in the library · 14,549 citations · publishing 2008-2026

Papers

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The quantum-classical complexity of consciousness and orchestrated objective reduction.

Frontiers in Human Neuroscience September 5, 2025 Alessandro Sergi, Antonino Messina, Gabriella Martino et al.

The Complexity of Consciousness and Orch OR Orch OR states that phenomena such as the discrete perception of time unfolding, the subjective wholeness of perception, spatio-temporal binding, causal free will [28], mechanisms of anesthesia, and the so-called "hard problem" are explainable aspects of consciousness. It organizes these phenomena within a systematic framework capable of explaining...

DOI: 10.3389/fnhum.2025.1630906 (opens in new tab) Full text (opens in new tab) Microtubules Complexity Consciousness Orch or +1

EEG-based characterization of auditory attention and meditation: an ERP and machine learning approach

Frontiers in Human Neuroscience August 26, 2025 Eyad Talal Attar 8 citations

Introduction This scientific investigation explored how meditation influences neural sound stimulus responses by employing EEG techniques during both meditative states and auditory oddball tasks. The study evaluated event-related potentials alongside theta, alpha and beta spectral power while employing machine learning techniques to distinguish meditative states from cognitive tasks. Methods...

DOI: 10.3389/fnhum.2025.1616456 (opens in new tab) Meditation Electroencephalography Cognitive psychology

Oceanic states of consciousness-an existential-neuroscience perspective.

Frontiers in Human Neuroscience August 11, 2025 Human-Friedrich Unterrainer 1 citation

Oceanic states of consciousness-characterized by ego dissolution, unity, and timelessness-have long occupied a liminal space between psychopathology and transcendence. This paper explores these states through the interdisciplinary lens of existential neuroscience, integrating insights from psychoanalysis, existentialism, affective neuroscience, and psychedelic research. Starting with the...

DOI: 10.3389/fnhum.2025.1653801 (opens in new tab) Full text (opens in new tab) Neurobiology Brain science Mystical experiences Oceanic states +6

Experiencing pain: electromagnetic waves, consciousness, and the mind.

Frontiers in Human Neuroscience July 24, 2025 Richard Ambron

Studies of nociception resulted in a theory in which the quality of pain - the suffering - arises when action potentials (APs) from the thalamus that encode information about an injury induce a long-term potentiation (LTP) at synapses on pyramidal neurons in a pain center (PC) within the anterior cingulate cortex (ACC). The LTP sensitizes transmission across the synapses via the activation of...

DOI: 10.3389/fnhum.2025.1568019 (opens in new tab) Full text (opens in new tab) Amygdala Pain Nucleus accumbens Anterior cingulate cortex +2

Individual alpha frequency tACS reduces static functional connectivity across the default mode network

Frontiers in Human Neuroscience May 14, 2025 Martín Carrasco-Gómez, Alejandra García-Colomo, Jesús Cabrera-Álvarez et al.

Introduction Research on the influence of transcranial alternating current stimulation over alpha functional connectivity (FC) is scarce, even when it poses as a potential treatment for various diseases. This study aimed to investigate the effects of individual alpha frequency tACS (IAF-tACS) on FC within the default mode network (DMN) in healthy individuals, particularly following the triple...

Resting-state BOLD temporal variability of the default mode network predicts spontaneous mind wandering, which is negatively associated with mindfulness skills.

Frontiers in Human Neuroscience January 22, 2025 Sara Sorella, Cristiano Crescentini, Alessio Matiz et al. 8 citations

Mind wandering (MW) encompasses both a deliberate and a spontaneous disengagement of attention from the immediate external environment to unrelated internal thoughts. Importantly, MW has been suggested to have an inverse relationship with mindfulness, a state of nonjudgmental awareness of present-moment experience. Although they are, respectively, associated with increased and decreased...

DOI: 10.3389/fnhum.2025.1515902 (opens in new tab) Full text (opens in new tab) Unprompted thoughts Spontaneous mind wandering Unwanted mental excursions Brain's resting activity +7

Long-term mindfulness meditation increases occurrence of sensory and attention brain states.

Frontiers in Human Neuroscience January 6, 2025 Daniel Yochai Panitz, Avi Mendelsohn, Joana Cabral et al. 5 citations

Interest has been growing in the use of mindfulness meditation (MM) as a therapeutic practice, as accumulating evidence highlights its potential to effectively address a range of mental conditions. While many fMRI studies focused on neural activation and functional connectivity during meditation, the impact of long-term MM practice on spontaneous brain activity, and on the expression of resting...

The strength of neural entrainment to electronic music correlates with proxies of altered states of consciousness.

Frontiers in Human Neuroscience 2025 Raquel Aparicio-Terrés, Samantha López-Mochales, Margarita Díaz-Andreu et al. 6 citations

In electronic music events, the driving four-on-the-floor music appears pivotal for inducing altered states of consciousness (ASCs). While various physiological mechanisms link repetitive auditory stimuli to ASCs, entrainment-a brainwave synchronization through periodic external stimuli-has garnered primary focus. However, there are no studies systematically exploring the relationship between...

The ConNECT approach: toward a comprehensive understanding of meaningful interpersonal moments in psychotherapy and beyond.

Frontiers in Human Neuroscience 2025 Niclas Kaiser, Juan Camilo Avendano-Diaz 4 citations

Relational neuroscience struggles to capture the complex dynamics of shared interpersonal moments, leading to gaps in understanding whether and how interdependencies between interacting persons translate into something meaningful. Current neuroscientific research often focuses on motor synchronization and cognition rather than the implicit relational qualities central to psychotherapy. We argue...

DOI: 10.3389/fnhum.2025.1549203 (opens in new tab) Full text (opens in new tab) Client-therapist interaction Convergence research Interpersonal dynamics Interpresence +3

Evidence of a hierarchical representation in bodily self-consciousness: the neural correlates of embodiment and presence in virtual worlds.

Frontiers in Human Neuroscience 2025 Evan Alexander Owens, Robert O Duncan 2 citations

Bodily Self-Consciousness (BSC) is the perception of bodily awareness that arises from the integration of neuronal signals in multiple sensory modalities. BSC is composed of embodiment (the perception of owning a body) and presence (the perception of being at a location). Converging lines of evidence suggest embodiment and presence are supported by different neural networks. Several models have...

DOI: 10.3389/fnhum.2025.1468947 (opens in new tab) Full text (opens in new tab) Bodily self-consciousness Embodiment Multisensory integration Presence +3

The intersection of near-death experiences (NDEs) and traumatic brain injury (TBI): neurobiological, phenomenological, and creative implications.

Frontiers in Human Neuroscience 2025 Diego Iacono, Gloria C Feltis

Traumatic brain injury (TBI) and near-death experiences (NDEs) represent profound disruptions in brain function, often associated with dramatic changes in consciousness, self-perception, and behavior. While these events are typically studied for their pathological consequences, a growing body of evidence suggests they may also trigger unexpected cognitive and creative enhancements in a subset...

DOI: 10.3389/fnhum.2025.1649513 (opens in new tab) Full text (opens in new tab) Human creativity Near-death experience nde Neurobiology Neuropharmacology +1

Macroscopic quantum effects in the brain: new insights into the fundamental principle underlying conscious processes.

Frontiers in Human Neuroscience 2025 Joachim Keppler

Empirical findings indicate that conscious states are inextricably linked to long-range synchronized activity patterns that result from phase transitions and exhibit the key features of self-organized criticality. This article builds a bridge between these neurophysiological characteristics of consciousness and the framework of quantum electrodynamics (QED), which provides the appropriate...

DOI: 10.3389/fnhum.2025.1676585 (opens in new tab) Full text (opens in new tab) Coherence domains Conscious processes Fundamental principle Macroscopic quantum effects +4

Determining the depth of meditation through frontal alpha asymmetry.

Frontiers in Human Neuroscience 2025 Dwivedi Krishna, Deepeshwar Singh, N K Manjunath

Electroencephalogram (EEG) alpha asymmetry has become a pivotal area of research for understanding functional hemispheric differences in neuroscience. To the best of our knowledge, the relationship between frontal alpha asymmetry (FAA) and the depth of meditation has yet to be thoroughly examined. To address this gap, the present cross-sectional study was conducted to explore the meditative...

DOI: 10.3389/fnhum.2025.1576642 (opens in new tab) Full text (opens in new tab) Visual analogue scale Depth of meditation Electroencephalogram Frontal alpha asymmetry +1

MDMA for PTSD and beyond: a new paradigm brings hope.

Frontiers in Human Neuroscience December 11, 2024 Scott Shannon, Jamarie Geller 3 citations

We are experiencing a mental health crisis of unprecedented proportions. Over the last two decades this crisis grew from a perfect storm of rising insurance deductibles, escalating social stressors, the COVID-19 pandemic, and a critical workforce deficiency. Perhaps no mental health arena has a greater shortfall of effective treatment options than Post-traumatic Stress Disorder (PTSD) as the...

Psychedelics in developmental stuttering to modulate brain functioning: a new therapeutic perspective?

Frontiers in Human Neuroscience June 19, 2024 Giuseppe Pasculli, Pierpaolo Busan, Eric S. Jackson et al. 5 citations

Developmental stuttering (DS) is a neurodevelopmental speech-motor disorder characterized by symptoms such as blocks, repetitions, and prolongations. Persistent DS often has a significant negative impact on quality of life, and interventions for it have limited efficacy. Herein, we briefly review existing research on the neurophysiological underpinnings of DS -specifically, brain metabolic and...

Is there an affective neuroscience of spirituality? The development and validation of the OCEANic feelings scale

Frontiers in Human Neuroscience January 17, 2024 Beate Schmautz, Jürgen Fuchshuber, Deborah Andres et al. 7 citations

Background: Oceanic feelings represent a phenomenological structure of affective sensations that characteristically involve feelings of self-dissolution and feelings of unity and transcendence. This study presents the preliminary version of a self-report instrument to measure individual dispositions toward oceanic feelings in order to enable further research within the concept of primary...

DOI: 10.3389/fnhum.2024.1329226 (opens in new tab) Confirmatory factor analysis Feeling Structural equation modeling Cronbach's alpha +10

Modelling phenomenological differences in aetiologically distinct visual hallucinations using deep neural networks

Frontiers in Human Neuroscience January 3, 2024 Keisuke Suzuki, Anil K. Seth, David J. Schwartzman 20 citations

Visual hallucinations (VHs) are perceptions of objects or events in the absence of the sensory stimulation that would normally support such perceptions. Although all VHs share this core characteristic, there are substantial phenomenological differences between VHs that have different aetiologies, such as those arising from Neurodegenerative conditions, visual loss, or psychedelic compounds....

DOI: 10.3389/fnhum.2023.1159821 (opens in new tab) Phenomenology philosophy Lewy body Cognitive psychology Visual hallucination +5

Transcranial focused ultrasound to the posterior cingulate cortex modulates default mode network and subjective experience: an fMRI pilot study.

Frontiers in Human Neuroscience 2024 Brian Lord, Joseph L. Sanguinetti, Lisannette Ruiz et al. 28 citations

Transcranial focused ultrasound (TFUS) is an emerging neuromodulation tool for temporarily altering brain activity and probing network functioning. The effects of TFUS on the default mode network (DMN) are unknown. The study examined the effects of transcranial focused ultrasound (TFUS) on the functional connectivity of the default mode network (DMN), specifically by targeting the posterior...

Advances in brain and religion studies: a review and synthesis of recent representative studies.

Frontiers in Human Neuroscience 2024 Patrick Mcnamara, Jordan Grafman 8 citations

We review and synthesize recent religion and brain studies and find that at a broad network neuroscience level, religious/spiritual experiences (RSEs) appear to depend crucially upon interactions between the default mode network (DMN), the frontoparietal network (FPN), and the salience network (SN). We see this general result as broadly consistent with Menon's et al. "Triple Network or...

Beyond awareness: the binding of reflexive mechanisms with the conscious mind: a perspective from default space theory.

Frontiers in Human Neuroscience 2024 Ravinder Jerath, Connor Beveridge 2 citations

How do reflexes operate so quickly with so much multimodal information on the environment? How might unconscious processes help reveal the nature of consciousness? The Default Space Theory of Consciousness (DST) offers a novel way to interpret these questions by describing how sensory inputs, cognitive functions, emotional states, and unconscious processes are integrated by a single unified...

An exploratory cluster-randomized controlled trial on mindfulness yoga's effectiveness in school-refusing children: reductions in SCAS-C physical injury fears and pulse rate.

Frontiers in Human Neuroscience 2024 Suguru Kawazu, Marie Amitani, Hajime Suzuki et al. 2 citations

School refusal is one of the serious problems with children's mental health, and various studies have examined its prevalence and factors among students. Although many studies suggested that anxiety and depression are deeply associated with school refusal, there is little agreement as to effective interventions. The purpose of this paper is to evaluate the efficacy and safety of mindfulness...

DOI: 10.3389/fnhum.2024.1468729 (opens in new tab) Full text (opens in new tab) Anxiety reduction Cognitive behavioral therapy Mindfulness yoga Pediatric mental health +1

Your brain on art, nature, and meditation: a pilot neuroimaging study.

Frontiers in Human Neuroscience 2024 Beatrix Krause-Sorio, Sergio Becerra, Prabha Siddarth et al. 1 citation

Exposure to art, nature, or meditation, all transcending human experiences, has beneficial effects on health and wellbeing. Focusing inward or watching art and nature videos elicits positive emotions that can help heal stress-related conditions. In a pilot functional magnetic resonance (fMRI) study, we explored the effect of watching digital art or nature videos compared to contemplating the...