In a pilot randomized controlled trial, twenty-two Guillain-Barré syndrome patients were assigned to either a yoga group receiving relaxation, pranayama, and guided meditation plus usual rehabilitation, or a control group receiving only usual care. Over three weeks, the yoga group showed significantly improved sleep quality compared to the control group. Pain, anxiety, depression, and overall functional status improved in both groups, but the differences between groups were not statistically significant. The findings suggest that adding yogic practices to standard rehabilitation can enhance sleep quality in GBS patients.
People with multiple sclerosis (PwMS), their care partners, MS clinicians, and mindfulness-based intervention (MBI) instructors identified four key themes for implementing online MBIs: structuring mindfulness to fit daily life, improving clinician awareness and advocacy to build referral pathways, ensuring validating group experiences through diverse participant composition and skilled instructor interactions, and providing resources for sustained engagement. PwMS valued having control to tailor MBIs to their needs and preferred diverse participant groups, though clinician guidance may be needed to foster self-agency. Shared decision-making among all knowledge users can enhance flexible online MBI programming.
Daily practice of internet-delivered mindfulness meditation for two weeks produced clinically important improvement in the mental component of quality-of-life among people with Ehlers-Danlos syndromes (EDS). Of 157 recruited from UK EDS charity mailing lists, 76 completed the intervention. The SF-36 mental component summary score showed a statistically significant change of medium effect size. Thematic analysis of interviews with 10 participants identified three themes: increased body awareness, reduction in pain intensity, and barriers to practice. The findings suggest online mindfulness meditation may be an acceptable therapy for pain in EDS, but controlled trials are needed to establish efficacy.
A mindfulness-based stress reduction program improved quality of life in individuals with mild to moderate traumatic brain injuries at least one year post-injury. Ten participants who completed the 12-week group program showed a mean improvement of 15.40 points on the SF-36 quality of life measure, compared to a decline of 1.67 points among three drop-outs used as controls. Improvements in the cognitive-affective domain of the Beck Depression Inventory II were also reported, while changes in overall depression and psychological distress approached but did not reach statistical significance. The authors argue the intervention encouraged acceptance and new perspectives on disability.