Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
September 9, 2026
Lisbeth Strandberg, Thiago P Fernandes, Irina I Shoshina et al.
Smoking cessation outcomes are heterogeneous, and factors associated with these differences are not fully understood. We examined longitudinal smoking trajectories across distinct smoking profiles and evaluated whether early craving and affective symptom changes were associated with verified abstinence. Participants in this observational cohort were classified as dependence-predominant or...
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
May 1, 2026
Marcelo Pinheiro Machado Adelino, Julia Diniz Grossi, Marcel Vella Nunes et al.
To synthesize evidence on pharmacological treatments for major depressive disorder (MDD) to inform updated Brazilian clinical guidelines. This overview included systematic reviews and meta-analyses published in the last 10 years, identified through MEDLINE, Cochrane Library, and SciELO. Eligible studies involved adults with MDD receiving pharmacological interventions. Risk of bias was assessed...
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
2026
Eduardo Aliende Perin, Nelson Carvas, Vinicius Tassoni Civile et al.
To evaluate the efficacy of mindfulness-based interventions for adults with obsessivecompulsive disorder. A systematic review and meta-analysis were conducted according to Cochrane Handbook guidelines. Two independent reviewers selected randomized controlled trials (RCTs) comparing mindfulness-based interventions with active control interventions, including cognitive/behavioral techniques and...
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
2025
Wagner Farid Gattaz, Marianna de Abreu Costa, Angélica Salatino-Oliveira et al.
There has been a call for neuroscientific studies of spiritual experiences due to their global prevalence, significant impact, and importance for understanding the mind-brain problem. Mediumship is a spiritual experience where individuals claim to communicate with or be influenced by deceased persons or non-material entities. We assessed whether mediums carry specific genetic alterations. We...
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
2021
Alvaro V Jardim, Dora V Jardim, Bruno Rasmussen Chaves et al.
54 citations
To conduct Brazil's first clinical trial employing 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for post-traumatic stress disorder (PTSD), given its high prevalence resulting from epidemic violence. Of 60 volunteers, four matched the inclusion & exclusion criteria. Three patients with PTSD secondary to sexual abuse (diagnosed by the Structured Clinical Interview for DSM-IV...
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
May 1, 2011
Alexander Moreira-Almeida, Etzel Cardeña
To review research articles in psychiatry and psychology involving Latin American populations and/or produced by Latin American scholars to investigate the differential diagnosis between spiritual/anomalous experiences and mental disorders in order to contribute to the validity of the International Classification of Diseases towards its 11th edition in this area. We searched electronic...
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
September 2009
Lara C Assis, Gislaine T Rezin, Clarissa M Comim et al.
Clinical findings suggest that ketamine may be used for the treatment of major depression. The present study aimed to compare behavioral effects and brain Creatine kinase activity in specific brain regions after administration of ketamine and imipramine in rats. Rats were acutely given ketamine or imipramine and antidepressant-like activity was assessed by the forced swimming test; Creatine...
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
September 2005
Sanjay J. Mathew, Kathryn Keegan, Lisa Smith
Recent evidence suggests that critical molecules in neurotrophic signaling cascades are long-term targets for currently available monoaminergic antidepressants. As chronic and severe mood disorders are characterized by impairments in neuronal resilience, pharmacological strategies that subserve a neuroprotective function might alter disorder pathophysiology and modify disease progression....
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
March 2003
Stella Pereira De Almeida, Maria Teresa Araujo Silva
As there are no studies about the use of ecstasy in Brazil, our aim was to identify the effects and patterns of use of this substance among users in the city of São Paulo. Subjects were recruited through the snowball technique. Fifty-two subjects of both genders who had been using ecstasy frequently and recently were interviewed. The instrument was a self-reported and anonymous questionnaire....