Restorative Neurology and Neuroscience
August 1, 2026
Perianen Ramasawmy, Luise Charlotte Heim, Elisabeth Fechner et al.
In this open-label single-arm study, we tested the preliminary therapeutic effects of a four-week mindfullness-based intervention (MBI) tailored for fibromyalgia, including weekly online group meetings and daily mindfulness practices. Forty-six patients completed the intervention. The primary outcome was pain intensity scored on a numerical rating scale (NRS). Secondary outcomes included verbal...
Clinical Journal of Pain
November 1, 2025
Perianen Ramasawmy, Andrea Antal, Olga L Gamboa Arana et al.
Mindfulness-based interventions (MBIs) appear to improve emotion regulation (ER) in disorders involving emotional dysregulation like fibromyalgia (FM). Despite the therapeutic potential of transcranial direct current stimulation (tDCS) in FM, its concurrent application with mindfulness meditation (MM) has not yet been explored. Potential synergistic effects may arise from aligning neural...
International journal of clinical and health psychology : IJCHP
February 3, 2023
Rebecca Divarco, Perianen Ramasawmy, Frank Petzke et al.
Background: Low intensity transcranial electrical stimulation (tES) and meditation are two promising, yet variable, non-pharmacological interventions. Growing research is investigating combined effects of both techniques on one's cognitive, emotional, and physical health. Objective: This article reviews the current research that combines tES and meditation interventions in healthy and diseased...
Frontiers in Medicine
2022
Perianen Ramasawmy, Sarah Khalid, Frank Petzke et al.
This double-blinded, randomized and sham-controlled pilot clinical trial aimed to investigate the preliminary clinical efficacy and feasibility of combining mindfulness meditation (MM) and transcranial direct current stimulation (tDCS) for pain and associated symptoms in patients with fibromyalgia syndrome (FMS). Included FMS patients (age: 33 to 70) were randomized to three different groups to...
bioRxiv
June 12, 2018
Aditya Singh, Tracy Erwin-Grabner, Grant Sutcliffe et al.
preprint
High frequency repetitive TMS (HF-rTMS) to the left dorsolateral prefrontal cortex (DLPFC) is an approved option for the treatment of depression, but there is also much variability in the resulting antidepressant response. This variability is believed to arise from various factors, an important one of which being the method by which rTMS is targeted to the optimal stimulation site in the left...