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James A Rickard

3 papers in the library · 2,647 citations · publishing 2016-2021

Papers

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Psilocybin with psychological support for treatment-resistant depression: six-month follow-up.

Psychopharmacology (Berl) November 8, 2017 R. L. Carhart-Harris, Mark Bolstridge, C. M. J. Day et al. 978 citations

RATIONALE: Recent clinical trials are reporting marked improvements in mental health outcomes with psychedelic drug-assisted psychotherapy. OBJECTIVES: Here, we report on safety and efficacy outcomes for up to 6 months in an open-label trial of psilocybin for treatment-resistant depression. METHODS: Twenty patients (six females) with (mostly) severe, unipolar, treatment-resistant major...

Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study.

Lancet Psychiatry May 17, 2016 Robin Carhart-Harris, Mark Bolstridge, James Rucker et al. 1,546 citations

BACKGROUND: Psilocybin is a serotonin receptor agonist that occurs naturally in some mushroom species. Recent studies have assessed the therapeutic potential of psilocybin for various conditions, including end-of-life anxiety, obsessive-compulsive disorder, and smoking and alcohol dependence, with promising preliminary results. Here, we aimed to investigate the feasibility, safety, and efficacy...