6 papers in the library · 1,722 citations · publishing 2016-2021
J Psychopharmacol February 18, 2021 Ben Sessa, Laurie Higbed, Steve O’Brien et al. 123 citations
First study of safety and tolerability of 3,4-methylenedioxymethamphetamine-assisted psychotherapy in patients with alcohol use disorder.
J Psychopharmacol June 15, 2020 Anna Borissova, Bart Ferguson, Matthew B. Wall et al. 37 citations
BACKGROUND: 3,4-Methylenedioxymethamphetamine (MDMA) is being actively researched as an adjunct to psychotherapy. It may be beneficial to trust, empathy and cooperative behaviour due to its acute prosocial effects. AIM: To test (a) the acute effects of MDMA on measures of empathy, trust and cooperative behaviour, and (b) subacute changes in mood three days after MDMA administration. METHODS: =7...
UNC Libraries April 22, 2020 Peter J. Hellyer, Luke T. J. Williams, Ben Sessa et al. 1 citation
Lysergic acid diethylamide (LSD), the prototypical “psychedelic,” may be unique among psychoactive substances. In the decades that followed its discovery, the magnitude of its effect on science, the arts, and society was unprecedented. LSD produces profound, sometimes life-changing experiences in microgram doses, making it a particularly powerful scientific tool. Here we sought to examine its...
Curr Biol April 13, 2016 Enzo Tagliazucchi, Leor Roseman, Mendel Kaelen et al. 531 citations
Lysergic acid diethylamide (LSD) is a non-selective serotonin-receptor agonist that was first synthesized in 1938 and identified as (potently) psychoactive in 1943. Psychedelics have been used by indigenous cultures for millennia [1]; however, because of LSD's unique potency and the timing of its discovery (coinciding with a period of major discovery in psychopharmacology), it is generally...
Eur Neuropsychopharmacol April 12, 2016 Mendel Kaelen, Leor Roseman, Joshua Kahan et al. 143 citations
Psychedelic drugs such as lysergic acid diethylamide (LSD) were used extensively in psychiatry in the past and their therapeutic potential is beginning to be re-examined today. Psychedelic psychotherapy typically involves a patient lying with their eyes-closed during peak drug effects, while listening to music and being supervised by trained psychotherapists. In this context, music is...
Proc Natl Acad Sci U S A April 11, 2016 Robin Carhart-Harris, Suresh Muthukumaraswamy, Leor Roseman et al. 887 citations
Lysergic acid diethylamide (LSD) is the prototypical psychedelic drug, but its effects on the human brain have never been studied before with modern neuroimaging. Here, three complementary neuroimaging techniques: arterial spin labeling (ASL), blood oxygen level-dependent (BOLD) measures, and magnetoencephalography (MEG), implemented during resting state conditions, revealed marked changes in...