ACS Omega
March 10, 2026
Dinesh Durán Jiménez, F. Vinckenbosch, J. Busink et al.
Nitrous oxide (N2O) is commonly used as a recreational drug, and the Dutch police have reported numerous traffic incidents related to its misuse. At the same time, the in vivo pharmacokinetics of N2O remain underexplored. In light of these facts, this study aimed to detect and quantify N2O in blood and saliva after inhalation exposure of a recreational dose. Consequently, a pilot in vivo study...
WIREs Forensic Science
November 7, 2023
F. Vinckenbosch, Dinesh Durán Jiménez, H. Helmerhorst et al.
Nitrous oxide (N2O), colloquially known as laughing gas, is a common recreational drug of abuse. The gas is inhaled in its undiluted form from a party balloon. Its intoxicating effects are described as dissociative and euphoric, accompanied by ataxia, hypoxia, and attenuated consciousness. Therefore, the recreational use of N2O appears irreconcilable with operating a vehicle in road traffic....
Psychopharmacology (Berl)
January 24, 2022
Kim van Oorsouw, S. W. Toennes, J. G. Ramaekers
71 citations
RATIONALE: Studies have suggested mental health improvements following the use of the psychotropic plant concoction ayahuasca in non-clinical and clinical samples. OBJECTIVES: The present observational study assessed depressive symptomatology in 20 clinically depressed patients (symptom score > 13 on the Beck's Depression Inventory) before attendance of an ayahuasca ceremony and 1 month and 1...
Psychopharmacology (Berl)
April 13, 2019
Malin V. Uthaug, R. Lancelotta, Kim van Oorsouw et al.
198 citations
A single inhalation of vapor from dried toad secretion containing 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) in a naturalistic setting is related to sustained enhancement of satisfaction with life, mindfulness-related capacities, and a decrement of psychopathological symptoms.
Addiction
August 8, 2006
J. G. Ramaekers, K. P. C. Kuypers, N. Samyn
90 citations
ABSTRACT Background 3,4‐methylenedioxymethamphetamine (MDMA) is currently one of the most popular drugs of abuse in Europe. Its increasing use over the last decade has led to concern regarding possible adverse effects on driving. The aims of the present study were to investigate the acute effects of MDMA on actual driving performance during the intoxication and withdrawal phase. Methods...
Journal of Psychopharmacology
March 1, 2006
C. T. J. Lamers, A. Bechara, M. Rizzo et al.
113 citations
Repeated ecstasy (MDMA) use is reported to impair cognition and cause increased feelings of depression and anxiety. Yet, many relevant studies have failed to control for use of drugs other than MDMA, especially marijuana (THC). To address these confounding effects we compared behavioural performance of 11 MDMA/THC users, 15 THC users and 15 non-drug users matched for age and intellect. We...