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Samantha L Baglot

2 papers in the library · publishing 2025-2026

Papers

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Dose-dependent effect of acute THC on extinction memory recall and fear renewal: a randomized, double-blind, placebo-controlled study.

Psychopharmacology February 1, 2026 Nicole L Zabik, Allesandra Iadipaolo, Craig A Peters et al.

Prior work from our lab and others demonstrates that the endocannabinoid system is a promising avenue for improving fear memory deficits in posttraumatic stress disorder (PTSD). Specifically, 7.5 mg of delta-9-tetrahydrocannabinol (THC) decreases fear responding in healthy adults and increases prefrontal cortex activation during extinction learning and fear renewal in adults with PTSD. The...

Cannabis produces acute hyperphagia in humans and rodents via increased reward valuation for, and motivation to, acquire food.

Proceedings of the National Academy of Sciences of the United States of America December 30, 2025 Catherine Hume, Carrie Cuttler, Samantha L Baglot et al.

With approximately 4% of the world's population using cannabis, there is a need to better understand its physiological effects. Cannabis consumption acutely promotes food intake ("the munchies") via delta-9-tetrahydrocannabinol-mediated activation of cannabinoid 1 receptors (CB1R); however, these appetitive effects have not been well characterized. We examined effects of cannabis vapor...