Savannah H M Lightfoot

2 papers in the library · publishing 2021-2026

Papers

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Acute and chronic cannabis vapor exposure produces immediate and delayed impacts on phases of fear learning in a sex specific manner.

Psychopharmacology February 1, 2026 Savannah H M Lightfoot, Andrei S Nastase, Gabriela Costa Lenz Cesar et al.

Current treatment options for PTSD have unreliable efficacy, with many individuals unable to achieve complete remission. Cannabis and cannabinoids that act through the endogenous cannabinoid (endocannabinoid) system to help promote trauma recovery by means of enhanced extinction learning are potential therapeutic, pharmacological candidates. Using a preclinical model of translationally-relevant...

DOI: 10.1007/s00213-025-06748-4 Full text Cannabis Acute Auditory fear conditioning Chronic +2

Pharmacokinetics and central accumulation of delta-9-tetrahydrocannabinol (THC) and its bioactive metabolites are influenced by route of administration and sex in rats.

Scientific Reports December 14, 2021 Samantha L Baglot, Catherine Hume, Gavin N Petrie et al.

Up to a third of North Americans report using cannabis in the prior month, most commonly through inhalation. Animal models that reflect human consumption are critical to study the impact of cannabis on brain and behaviour. Most animal studies to date utilize injection of delta-9-tetrahydrocannabinol (THC; primary psychoactive component of cannabis). THC injections produce markedly different...

DOI: 10.1038/s41598-021-03242-7 Full text