Neuropsychopharmacology
October 29, 2026
Stephanie Lake, Elisa Pabon, Samantha L Baglot et al.
Cannabis use is rising among women. Studies suggest females are more sensitive to the intoxicating and misuse-related effects of delta-9-tetrahydrocannabinol (THC). While preclinical studies point to sex-specific development of tolerance, this has not been translated to humans. In this randomized, double-blind, placebo-controlled crossover study, 44 participants (22 F) smoked three cannabis...
Psychophysiology
February 2022
Elisa Pabon, Frederica Rockwood, Greg J Norman et al.
Cannabis is the most commonly used psychotropic drug in the United States, after alcohol. Despite its apparent sedative and calming effects, cannabis and its main psychoactive constituent, ∆9 -tetrahydrocannabinol (THC) can produce serious adverse effects including tachycardia and anxiety. These effects can be especially pronounced in women, who remain underrepresented in clinical cannabinoid...
Neuropsychopharmacology
October 1, 2020
Kirsten C. S. Adam, Manoj K. Doss, Elisa Pabon et al.
2 citations
With the increasing prevalence of legal cannabis use and availability, there is an urgent need to identify cognitive impairments related to its use. It is widely believed that cannabis, or its main psychoactive component Δ9-tetrahydrocannabinol (THC), impairs working memory, i.e., the ability to temporarily hold information in mind. However, our review of the literature yielded surprisingly...
bioRxiv (Cold Spring Harbor Laboratory)
September 23, 2019
Kirsten C. S. Adam, Manoj K. Doss, Elisa Pabon et al.
2 citations
preprint
Abstract With the increasing prevalence of legal cannabis use and availability, there is an urgent need to identify cognitive impairments related to its use. It is widely believed that cannabis, or its main psychoactive component Δ 9 -tetrahydrocannabinol (THC), impairs working memory, i.e., the ability to temporarily hold information in mind. However, our review of the literature yielded...
Journal of Psychopharmacology
September 1, 2019
Elisa Pabon, Harriet de Wit
Acute consumption of cannabis or its primary psychoactive ingredient ∆9-tetrahydrocannabinol has been shown to impair memory, reaction time, time perception, and attention. However, it is difficult to measure these impairments in a brief test that can be used in a non-laboratory setting. We aim to develop and validate a prototype for a mobile phone application to measure...