Journal of cardiothoracic surgery
May 27, 2025
Joshua V. Ross, Thomas Jan, Deane Smith et al.
1 citation
Studies have not explored consciousness during deep hypothermic circulatory arrest (DHCA). However, as studies in cardiac arrest have identified a spectrum of consciousness, we sought to establish the feasibility of studying consciousness during DHCA. This was a prospective study across 10 hospitals with 36 DHCA patients undergoing thoracic aortic aneurysm repair or pulmonary endarterectomy. A...
Resuscitation
October 1, 2023
Sam Parnia, Tara Keshavarz Shirazi, Jignesh Patel et al.
64 citations
Cognitive activity and awareness during cardiac arrest (CA) are reported but ill understood. This first of a kind study examined consciousness and its underlying electrocortical biomarkers during cardiopulmonary resuscitation (CPR). In a prospective 25-site in-hospital study, we incorporated a) independent audiovisual testing of awareness, including explicit and implicit learning using a...
Annals of the New York Academy of Sciences
February 18, 2022
Sam Parnia, Stephen G. Post, Matthew T. Lee et al.
68 citations
An inadvertent consequence of advances in stem cell research, neuroscience, and resuscitation science has been to enable scientific insights regarding what happens to the human brain in relation to death. The scientific exploration of death is in large part possible due to the recognition that brain cells are more resilient to the effects of anoxia than assumed. Hence, brain cells become...
QJM : monthly journal of the Association of Physicians
November 9, 2016
Sam Parnia
Transcendental mystical or spiritual experiences close to death have been described for millennia. However, following the birth of modern intensive care medicine four decades ago, the specific term ‘near-death experience’ (NDE) was coined.1 Current research indicates that, regardless of cultural background, adults and young children (<3 years) have described comparable experiences in...