5 papers in the library · 194 citations · publishing 2012-2018
PLoS One March 22, 2018 B. Roth, Simon Gibbons, Warunya Arunotayanun et al. correction
[This corrects the article DOI: 10.1371/journal.pone.0059334.].
Forensic Science International October 2016 Shruti Beharry, Simon Gibbons
The purpose of this review is to identify emerging or new psychoactive substances (NPS) by undertaking an online survey of the UK NPS market and to gather any data from online drug forums and published literature. Drugs from four main classes of NPS were identified: psychostimulants, dissociative anaesthetics, hallucinogens (phenylalkylamine-based and lysergamide-based materials) and finally...
PLoS One June 14, 2016 Bryan L. Roth, Simon Gibbons, Warunya Arunotayanun et al. 153 citations
In this paper we determined the pharmacological profiles of novel ketamine and phencyclidine analogues currently used as 'designer drugs' and compared them to the parent substances via the resources of the National Institute of Mental Health Psychoactive Drug Screening Program. The ketamine analogues methoxetamine ((RS)-2-(ethylamino)-2-(3-methoxyphenyl)cyclohexanone) and 3-MeO-PCE...
Bioorganic & Medicinal Chemistry Letters June 1, 2013 Warunya Arunotayanun, Jeffrey W Dalley, Xi-Ping Huang et al. 41 citations
Novel Psychoactive Drugs (NPD) can be sold without restriction and are often synthetic analogues of controlled drugs. The tryptamines are an important class of NPD as they bind to the various serotonin (5-HT) receptor subtypes and cause psychosis and hallucinations that can lead to injury or death through misadventure. Here we report on the structure elucidation and receptor binding profiles of...
Current Drug Abuse Reviews December 1, 2012 Carolyn B McNabb, Bruce R. Russell, Daniele Caprioli et al.
A recent and dramatic increase in the emergence of novel psychoactive substances ('legal highs') has left many governments unable to provide a timely response to an increasing number of potentially harmful drugs now available to the public. In response to this rapid increase in lawful drug use, the UK government intends to implement temporary class drug orders, whereby substances with a...