Brain : a journal of neurology
June 12, 2025
Marwan H Othman, Attila Géry Toury-Puel, Karen Irgens Tanderup Hansen et al.
7 citations
In the intensive care unit (ICU), management of unresponsive patients with brain injury focuses on preventing secondary brain damage. Therapeutic strategies that directly promote the recovery of consciousness are urgently needed. In an investigator-initiated, randomized, placebo-controlled, double-blind, cross-over trial, we studied the effects of apomorphine and methylphenidate in ICU patients...
Brain Communications
June 22, 2021
Costanza Peinkhofer, Charlotte Martial, Héléna Cassol et al.
49 citations
Abstract Near-death experiences are known from all parts of the world, various times and numerous cultural backgrounds. This universality suggests that near-death experiences may have a biological origin and purpose. Adhering to a preregistered protocol, we investigate the hypothesis that thanatosis, aka death-feigning, a last-resort defense mechanism in animals, is the evolutionary origin of...
Current Neurology and Neuroscience Reports
July 27, 2019
Costanza Peinkhofer, Jens P Dreier, Daniel Kondziella
45 citations
Purpose of reviewNear-death experiences (NDEs) are conscious perceptual experiences, including self-related emotional, spiritual, and mystical experiences, occurring in close encounters with death or in non-life-threatening situations. The origin of NDEs remains unknown. Here, we review recent advances in the understanding of NDE semiology and pathophysiology.Recent findingsRecent prospective...