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P T Thomas

1 paper in the library · 12 citations · publishing 1995

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Comparison of the hallucinogenic indole alkaloids ibogaine and harmaline for potential immunomodulatory activity.

Pharmacology June 1, 1995 Robert V. House, P T Thomas, Hemendra N. Bhargava 12 citations

The immunomodulatory potential of the indole alkaloids ibogaine and harmaline was examined in a panel of in vitro immune function assays. These assays were chosen to assess T-cell regulatory and effector function, B-cell function, macrophage function, and natural killer-cell function. The in vitro exposure to either ibogaine or harmaline resulted in a dose-related suppression of all immune...