Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug
Brazilian Journal of Medical and Biological Research April 1, 2006 Antônio Waldo Zuardi, José A. Crippa, Jaime E. C. Hallak et al. 411 citations
A high dose of delta9-tetrahydrocannabinol, the main Cannabis sativa (cannabis) component, induces anxiety and psychotic-like symptoms in healthy volunteers. These effects of delta9-tetrahydrocannabinol are significantly reduced by cannabidiol (CBD), a cannabis constituent which is devoid of the typical effects of the plant. This observation led us to suspect that CBD could have anxiolytic...