Study of the in vitro and in vivo metabolism of the tryptamine 5‐MeO‐MiPT using human liver microsomes and real case samples
Drug Testing and Analysis July 5, 2017 Katharina Elisabeth Grafinger, Marianne Hädener, Stefan König et al. 31 citations
Abstract The synthetic tryptamine 5‐methoxy‐ N ‐methyl‐ N ‐isopropyltryptamine (5‐MeO‐MiPT) has recently been abused as a hallucinogenic drug in Germany and Switzerland. This study presents a case of 5‐MeO‐MiPT intoxication and the structural elucidation of metabolites in pooled human liver microsomes (pHLM), blood, and urine. Microsomal incubation experiments were performed using pHLM to...