Jérémy Carlier

2 papers in the library · publishing 2022-2026

Papers

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Toxicokinetics and analytical toxicology of four N, N-dimethyltryptamine derivatives studied in human in vitro systems and in vivo by means of zebrafish embryos.

Archives of Toxicology September 21, 2026 Gloria Daziani, Lea Wagmann, Matthias D. Kroesen et al.

N,N-Dimethyltryptamine (DMT) is a naturally occurring substituted tryptamine used as a psychedelic drug for ritual purposes by various cultures. Derivatives were already found on the drug of abuse market, such as N1-tert-butoxycarbonyl-N,N-dimethyltryptamine (DMT-Boc). The aim of the current study was to investigate the toxicokinetics of DMT-Boc and three related DMT derivatives, by name...

DOI: 10.1007/s00204-026-04552-3 Full text Metabolism New psychoactive substances Toxicokinetics Tryptamines

Biomarkers of 4-hydroxy-N,N-methylpropyltryptamine (4-OH-MPT) intake identified from human hepatocyte incubations

Expert Opinion on Drug Metabolism & Toxicology December 2, 2022 Jérémy Carlier, Sara Malaca, Marilyn A. Huestis et al.

ABSTRACT Background 4-Hydroxy-N,N-methylpropyltryptamine (4-OH-MPT) is a psychedelic tryptamine whose use is regulated in several countries. Due to unspecific effects, consumption can be ascertained only through toxicological analyses. However, the trace amounts of tryptamines are usually challenging to detect in biological samples. 4-OH-MPT metabolism was characterized to identify optimal...

DOI: 10.1080/17425255.2022.2166826 Full text