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B.b. Brodie

1 paper in the library · 60 citations · publishing 1957

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LSD-Like Effects Elicited by Reserpine in Rabbits Pretreated With Iproniazid.

Experimental Biology and Medicine March 1, 1957 Parkhurst A. Shore, B.b. Brodie 60 citations

1. Administration of reserpine to rabbits pretreated with the monoamine oxidase inhibitor, iproniazid, causes excitation and sympathomimetic effects similar to those observed after administration of LSD or high doses of 5-hydroxytryptophan. These effects are associated with the presence of a high concentration of free serotonin in the brain. The observations are consistent with the concept that...