Frontiers in Psychiatry
August 31, 2020
Giovanni Martinotti, Attilio Negri, Stefania Schiavone et al.
22 citations
In this study, we described the acute psychiatric presentations related to recreational drug use in subjects on holiday in Ibiza. The use of psychoactive substances was characterized by poly-use of both traditional and novel substances, with several psychopathological consequences. Future research should focus on a better understanding of the psychopathological effects of specific substances,...
International Journal of Molecular Sciences
March 12, 2019
Stefania Schiavone, Margherita Neri, Angela Bruna Maffione et al.
22 citations
Several mechanisms underlying 3,4-Methylenedioxy-N-methylamphetamine (MDMA) neurotoxicity have been proposed, including neurochemical alterations and excitotoxicity mediated by reactive oxygen species (ROS), nitric oxide (NO), and reactive nitrogen species (RNS). However, ROS, NO, and RNS sources in the brain are not fully known. We aimed to investigate possible alterations in the expression of...
International Clinical Psychopharmacology
September 1, 2011
Silvia Sorce, Stefania Schiavone, Paolo Tucci et al.
The 15th Biennial Winter Workshop in Psychoses, 15–18 November 2009, Barcelona, Spain: DRUG INDUCED PSYCHOSES
The Journal of Neuroscience
August 25, 2010
Silvia Sorce, Stefania Schiavone, Paolo Tucci et al.
Subanesthetic doses of NMDA receptor antagonist ketamine induce schizophrenia-like symptoms in humans and behavioral changes in rodents. Subchronic administration of ketamine leads to loss of parvalbumin-positive interneurons through reactive oxygen species (ROS), generated by the NADPH oxidase NOX2. However, ketamine induces very rapid alterations, in both mice and humans. Thus, we have...