2 papers in the library · publishing 2010-2011
International Clinical Psychopharmacology September 1, 2011 Silvia Sorce, Stefania Schiavone, Paolo Tucci et al.
The 15th Biennial Winter Workshop in Psychoses, 15–18 November 2009, Barcelona, Spain: DRUG INDUCED PSYCHOSES
The Journal of Neuroscience August 25, 2010 Silvia Sorce, Stefania Schiavone, Paolo Tucci et al.
Subanesthetic doses of NMDA receptor antagonist ketamine induce schizophrenia-like symptoms in humans and behavioral changes in rodents. Subchronic administration of ketamine leads to loss of parvalbumin-positive interneurons through reactive oxygen species (ROS), generated by the NADPH oxidase NOX2. However, ketamine induces very rapid alterations, in both mice and humans. Thus, we have...