Increased iNOS and Nitrosative Stress in Dopaminergic Neurons of MDMA-Exposed Rats
International Journal of Molecular Sciences March 12, 2019 Stefania Schiavone, Margherita Neri, Angela Bruna Maffione et al. 22 citations
Several mechanisms underlying 3,4-Methylenedioxy-N-methylamphetamine (MDMA) neurotoxicity have been proposed, including neurochemical alterations and excitotoxicity mediated by reactive oxygen species (ROS), nitric oxide (NO), and reactive nitrogen species (RNS). However, ROS, NO, and RNS sources in the brain are not fully known. We aimed to investigate possible alterations in the expression of...