bioRxiv (Cold Spring Harbor Laboratory)
August 10, 2026
Aedan O'Shea, Natasha L. Mason, Jacco Briede et al.
preprint
Abstract Psilocybin acutely alters neurotrophic, neurochemical, and immune markers, but the relationships between these responses and circulating microRNAs (miRNAs), i.e. non-coding RNAs that regulate post-transcriptional gene expression, remain unclear. In a randomized, double-blind, placebo-controlled study of 62 healthy adults who received psilocybin (0.17 mg/kg) or placebo, we previously...
International Journal of Environmental Research and Public Health
July 21, 2023
Guido Huisman, Maximilian Menke, Oliver Grundmann et al.
13 citations
) is a Southeast Asian plant containing various alkaloids that induce pharmacological effects in humans. In Western countries, online vendors sell a variety of different kratom strains which are marketed to have distinct effect profiles. However, as of yet such marketing claims are unsubstantiated, and therefore the current study investigated whether differently colored kratom products can...
Psychopharmacology (Berl)
March 29, 2022
Manon M.j. van den Berg, Igor Magaraggia, Rudy Schreiber et al.
14 citations
How to account for hallucinations in the interpretation of the antidepressant effects of psychedelics: a translational framework.
Neurobiology of Learning and Memory
May 25, 2021
Igor Magaraggia, Zilla Kuiperes, Rudy Schreiber
49 citations
The high symptomatic and biological heterogeneity of major depressive disorder (MDD) makes it very difficult to find broadly efficacious treatments that work against all symptoms. Concentrating on single core symptoms that are biologically well understood might consist of a more viable approach. The Research Domain Criteria (RDoC) framework is a trans-diagnostic dimensional approach that...