This dissertation has taken an interdisciplinary approach to investigate and give insights into psilocybin’s neurobiological underpinnings. Psilocybin is a naturally occurring serotonergic psychedelic and is the main ingredient in hallucinogenic mushrooms. Research has demonstrated that psilocybin profoundly activates the serotonin (5-hydroxytryptamine) 2A (5-HT2A) receptors. Upon activation of...