Anti-Inflammatory Effects of Four Psilocybin-Containing Magic Mushroom Water Extracts in vitro on 15-Lipoxygenase Activity and on Lipopolysaccharide-Induced Cyclooxygenase-2 and Inflammatory Cytokines in Human U937 Macrophage Cells
Sanah Malomile Nkadimeng, Christiaan Ml Steinmann, J.n. Eloff
Journal of Inflammation Research August 1, 2021 DOI: 10.2147/jir.s317182 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Laboratory study Peer reviewed |
|---|---|
| Population | Psilocybin-containing magic mushrooms |
| Topics | Psilocybin |
| Keywords | Lipopolysaccharide U937 cell Cyclooxygenase Inflammation Pharmacology Tetradecanoylphorbol acetate Lipoxygenase Biochemistry |
| Citations | 77 |
| Key points | Hot-water extracts of four psilocybin-containing magic mushrooms down-regulate pro-inflammatory mediators, indicating potential anti-inflammatory effects. |
Abstract
The study suggested that the hot-water extracts of the four psilocybin-containing magic mushrooms have potential anti-inflammatory effects executed by down-regulating pro-inflammatory mediators.