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Jianghui Xu

3 papers in the library · 80 citations · publishing 2018-2024

Papers

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Changes in information integration and brain networks during propofol-, dexmedetomidine-, and ketamine-induced unresponsiveness.

British Journal of Anaesthesia March 1, 2024 Zhenhu Liang, Yu Chang, Xiaoge Liu et al. 10 citations

Information integration and network science are important theories for quantifying consciousness. However, whether these theories propose drug- or conscious state-related changes in EEG during anaesthesia-induced unresponsiveness remains unknown. A total of 72 participants were randomised to receive i.v. infusion of propofol, dexmedetomidine, or ketamine at a constant infusion rate until loss...

DOI: 10.1016/j.bja.2023.11.033 (opens in new tab) Full text (opens in new tab) Ketamine Brain network Dexmedetomidine Electroencephalography +1

Disrupted neural variability during propofol-induced sedation and unconsciousness.

Human Brain Mapping November 2018 Zirui Huang, Jun Zhang, Jinsong Wu et al.

Variability quenching is a widespread neural phenomenon in which trial-to-trial variability (TTV) of neural activity is reduced by repeated presentations of a sensory stimulus. However, its neural mechanism and functional significance remain poorly understood. Recurrent network dynamics are suggested as a candidate mechanism of TTV, and they play a key role in consciousness. We thus asked...

DOI: 10.1002/hbm.24304 (opens in new tab) Full text (opens in new tab) Anesthesia Consciousness FMRI Neural variability +5

Breakdown in the temporal and spatial organization of spontaneous brain activity during general anesthesia

Human Brain Mapping January 28, 2018 Jianfeng Zhang, Zirui Huang, Yali Chen et al. 70 citations

Which temporal features that can characterize different brain states (i.e., consciousness or unconsciousness) is a fundamental question in the neuroscience of consciousness. Using resting-state functional magnetic resonance imaging (rs-fMRI), we investigated the spatial patterns of two temporal features: the long-range temporal correlations (LRTCs), measured by power-law exponent (PLE), and...

DOI: 10.1002/hbm.23984 (opens in new tab) Unconsciousness Wakefulness Spatial variability Electroencephalography