Mindfulness
2026
Marianne Holopainen, Mirka Hintsanen, Jari Lahti et al.
There is currently a lack of empirical studies investigating whether specific personality traits moderate the effects of mindfulness-based interventions (MBIs) on distinct adolescent mental health outcomes. This study examined how personality traits from a five-factor model (agreeableness, conscientiousness, emotional stability, extraversion, and openness to experience) moderate the effects of...
British Journal of Anaesthesia
August 1, 2023
Katja Valli, Linda Radek, Roosa E Kallionpää et al.
Anaesthetic-induced unresponsiveness and non-rapid eye movement (NREM) sleep share common neural pathways and neurophysiological features. We hypothesised that these states bear resemblance also at the experiential level. We compared, in a within-subject design, the prevalence and content of experiences in reports obtained after anaesthetic-induced unresponsiveness and NREM sleep. Healthy males...
The Journal of neuroscience : the official journal of the Society for Neuroscience
June 28, 2023
Oskari Kantonen, Lauri Laaksonen, Michael Alkire et al.
Establishing the neural mechanisms responsible for the altered global states of consciousness during anesthesia and dissociating these from other drug-related effects remains a challenge in consciousness research. We investigated differences in brain activity between connectedness and disconnectedness by administering various anesthetics at concentrations designed to render 50% of the subjects...
The Journal of neuroscience : the official journal of the Society for Neuroscience
February 24, 2021
Annalotta Scheinin, Oskari Kantonen, Michael Alkire et al.
92 citations
What happens in the brain when conscious awareness of the surrounding world fades? We manipulated consciousness in two experiments in a group of healthy males and measured brain activity with positron emission tomography. Measurements were made during wakefulness, escalating and constant levels of two anesthetic agents (experiment 1, n = 39), and during sleep-deprived wakefulness and non-rapid...
British Journal of Anaesthesia
July 1, 2018
Linda Radek, Roosa E Kallionpää, M Karvonen et al.
Experiences during anaesthetic-induced unresponsiveness have previously been investigated by interviews after recovery. To explore whether experiences occur during drug administration, we interviewed participants during target-controlled infusion (TCI) of dexmedetomidine or propofol and after recovery. Healthy participants received dexmedetomidine (n=23) or propofol (n=24) in stepwise...