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Yuta Takahashi

2 papers in the library · 21 citations · publishing 2025-2026

Papers

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Effects of 4-position substitutions of diphenidine on blood-brain barrier penetration and dopamine release in the nucleus accumbens of rats.

Forensic Toxicology July 1, 2026 Yuta Takahashi, Katsuhiro Okuda, Kazuo Matsubara et al.

Diphenidine (DPD) is a dissociative novel psychoactive substance (NPS) structurally related to phencyclidine and ketamine. Although DPD is legally regulated in Japan and several other countries, analogues sharing the core scaffold are not comprehensively regulated. Therefore, it is possible that analogues with minor scaffold modifications may continue to emerge. This study examined the effects...

Digital twin brain simulator for real-time consciousness monitoring and virtual intervention using primate electrocorticogram data.

NPJ digital medicine February 10, 2025 Yuta Takahashi, Hayato Idei, Misako Komatsu et al. 21 citations

At the forefront of bridging computational brain modeling with personalized medicine, this study introduces a novel, real-time, electrocorticogram (ECoG) simulator, based on the digital twin brain concept. Utilizing advanced data assimilation techniques, specifically a Variational Bayesian Recurrent Neural Network model with hierarchical latent units, the simulator dynamically predicts ECoG...