Digital twin brain simulator for real-time consciousness monitoring and virtual intervention using primate electrocorticogram data.
NPJ digital medicine February 10, 2025 Yuta Takahashi, Hayato Idei, Misako Komatsu et al. 21 citations
At the forefront of bridging computational brain modeling with personalized medicine, this study introduces a novel, real-time, electrocorticogram (ECoG) simulator, based on the digital twin brain concept. Utilizing advanced data assimilation techniques, specifically a Variational Bayesian Recurrent Neural Network model with hierarchical latent units, the simulator dynamically predicts ECoG...