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K Herrick-Davis

1 paper in the library · 78 citations · publishing 1995

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Radioligand-binding study of noribogaine, a likely metabolite of ibogaine.

Brain Research March 27, 1995 S M Pearl, K Herrick-Davis, M Teitler et al. 78 citations

Radioligand-binding studies were performed to ascertain the actions of noribogaine, a suspected metabolite of ibogaine, on opioid receptors. Consistent with previous results, ibogaine showed highest affinity for kappa opioid receptors (Ki = 3.77 +/- 0.81 microM), less affinity for mu receptors (Ki = 11.04 +/- 0.66 microM) and no affinity for delta receptors (Ki > 100 microM). Noribogaine showed...