Effects of 18-methoxycoronaridine on acute signs of morphine withdrawal in rats.
Neuroreport May 11, 1998 B Rho, Stanley D Glick 35 citations
Ibogaine, an alkaloid found in the root bark of the African shrub Tabernanthe iboga, has been claimed to interrupt opioid dependence in humans; in animals, it has been shown to inhibit morphine self-administration and to attenuate signs of morphine withdrawal. However, ibogaine has some neurotoxicity, and because of this, efficacious and safer congeners of ibogaine have been sought,...