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Brian H Silverstein

3 papers in the library · 11 citations · publishing 2015-2025

Papers

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Intravenous psilocybin induces dose-dependent changes in functional network organization in rat cortex

Translational Psychiatry March 25, 2025 Brian H Silverstein, Nicholas Kolbman, Amanda Nelson et al. 8 citations

Psilocybin produces an altered state of consciousness in humans and is associated with complex spatiotemporal changes in cortical networks. Given the emphasis on rodent models for mechanistic studies, there is a need for characterization of the effect of psilocybin on cortex-wide network dynamics. Previous electroencephalographic studies of psychedelics in rodents have primarily used sparse...

Psilocybin induces dose-dependent changes in functional network organization in rat cortex

bioRxiv (Cold Spring Harbor Laboratory) February 12, 2024 Brian H Silverstein, Nicholas Kolbman, Amanda Nelson et al. 3 citations preprint

Abstract Psilocybin produces an altered state of consciousness in humans and is associated with complex spatiotemporal changes in brain networks. Given the emphasis on rodent models for mechanistic studies, there is a need for characterization of the effect of psilocybin on brain-wide network dynamics. Previous rodent studies of psychedelics, using electroencephalogram, have primarily been done...

P3b, consciousness, and complex unconscious processing.

Cortex September 25, 2015 Brian H Silverstein, Michael Snodgrass, Howard Shevrin et al.

How can perceptual consciousness be indexed in humans? Recent work with ERPs suggests that P3b, a relatively late component, may be a neural correlate of consciousness (NCC). This proposal dovetails with currently prevailing cognitive theory regarding the nature of conscious versus unconscious processes, which holds that the latter are simple and very brief, whereas consciousness is ostensibly...