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Hiroyuki Kamakura

2 papers in the library · 14 citations · publishing 2008

Papers

[Authentication and ultra performance liquid chromatography (UPLC)/MS analysis of magic mint, Salvia divinorum and its related plants].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan January 1, 2008 Takuro Maruyama, Hiroyuki Kamakura, Ruri Kikura-Hanajiri et al. 14 citations

Before Salvia divinorum was regulated under Japan's Pharmaceutical Affairs Law, commercial Salvia cultivars sold in Japan were tested for the hallucinogen salvinorin A. Ultra performance liquid chromatography/mass spectrometry showed that none of the cultivars contained salvinorin A, whereas S. divinorum leaves and its processed product "concentrated salvia" contained 0.19% to 0.58% of the compound. A DNA-based authentication method using amplification refractory mutation system clearly distinguished S. divinorum from the cultivars. The authors conclude that this authentication method is simple and accurate, making it useful for practical regulation.

DOI: 10.1248/yakushi.128.179 (opens in new tab) Full text (opens in new tab) Salvia divinorum Salvinorin a Magic mint Psychoactive plant +19

[Analytical data of designated substances (Shitei-Yakubutsu) controlled by the Pharmaceutical Affairs Law in Japan, part I: GC-MS and LC-MS].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan June 1, 2008 Ruri Kikura-Hanajiri, Maiko Kawamura, Nahoko Uchiyama et al.

Japan's Ministry of Health, Labor and Welfare amended the Pharmaceutical Affairs Law in 2006 to control 31 non-controlled psychotropic substances and one plant as "Designated Substances" as of April 2007, with five more compounds added in January 2008. These substances had been sold as video cleaners, incense, and reagents via the Internet or in video shops. The authors developed simultaneous analytical methods using gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS) and present retention times, UV spectra, and mass spectrometry data for these substances.

DOI: 10.1248/yakushi.128.971 (opens in new tab) Full text (opens in new tab)