Nature Medicine
February 1, 2024
Kirsten Cherian, Jackob N. Keynan, Lauren Anker et al.
66 citations
Traumatic brain injury (TBI) is a leading cause of disability. Sequelae can include functional impairments and psychiatric syndromes such as post-traumatic stress disorder (PTSD), depression and anxiety. Special Operations Forces (SOF) veterans (SOVs) may be at an elevated risk for these complications, leading some to seek underexplored treatment alternatives such as the oneirogen ibogaine, a...
Frontiers in pain research (Lausanne, Switzerland)
2023
Jonathan Dickinson, Jose Adalberto Dominguez Inzunza, Liliana Perez-Villa et al.
3 citations
Brachial plexus nerve root avulsion results from complete separation of the nerve root from the spinal cord and is one of the most challenging types of neuropathic pain, coinciding with motor, sensory and autonomic deficits. The severe pain and typical impossibility of root reattachment often leads to requests for amputation. Ibogaine is an indole alkaloid producing psychoactive effects through...
Journal of Evolutionary Psychology
March 30, 2020
Claire Wilson, Trevor Millar, Zak Matieschyn
11 citations
Abstract Ibogaine is a naturally occurring psychedelic medicine with anti-addictive properties. While research on ibogaine is limited, several observational studies have shown ibogaine can mitigate opioid withdrawal, as seen with reductions in clinical and subjective opioid withdrawal scores and reduced drug use severity (Noller, Frampton, & Yazar-Klosinski, 2018; Brown & Alper 2018)....
Journal of Psychoactive Drugs
2016
Laurie Cloutier-Gill, Evan Wood, Trevor Millar et al.
22 citations
Opioid use disorders (OUD) translate into major health, social, and economic consequences. Opioid agonist medications, which generally require long-term administration, are the mainstay pharmacological treatment of OUD. However, a large proportion of individuals with OUD either refuse or fail to respond to these therapies. Ibogaine, a naturally occurring substance found in the Tabernanthe iboga...