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Sizhen Su

3 papers in the library · 2 citations · publishing 2022-2025

Papers

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Psychoactive substances: novel molecular insights and therapeutic potential for Alzheimer's disease.

Translational neurodegeneration July 25, 2025 Chonglei Fu, Xuehui Li, Xiaoxing Liu et al. 2 citations

Alzheimer's disease (AD) is a major neurodegenerative disorder that causes severe cognitive decline and poses a significant burden on global health systems. Despite extensive research, effective treatments to stop neurodegeneration or promote neuronal regeneration in AD remain elusive. Psychoactive substances as modulators of neurophysiological functions, have received increased attention in...

DOI: 10.1186/s40035-025-00498-1 (opens in new tab) Full text (opens in new tab) Alzheimer's disease Challenges Molecular insights Psychoactive substances +6

Blunted superior temporal gyrus activity to negative emotional expression after mindfulness-based cognitive therapy for late-life depression.

Frontiers in Aging Neuroscience 2022 Weijian Liu, Hui Li, Xiao Lin et al.

Facial emotion recognition plays an important role in social functioning. Patients with late-life depression (LLD) often have abnormal facial emotion recognition. Mindfulness-based cognitive therapy (MBCT) is beneficial in treating depression. This study examined whether MBCT can act as an effective augmentation of antidepressants and improve facial emotion recognition in patients with LLD and...

DOI: 10.3389/fnagi.2022.1001447 (opens in new tab) Full text (opens in new tab) Facial emotion recognition Late-life depression lld Neural mechanism

Mindfulness-Based Cognitive Therapy Regulates Brain Connectivity in Patients With Late-Life Depression.

Frontiers in Psychiatry 2022 Hui Li, Wei Yan, Qianwen Wang et al.

Late-life depression (LLD) is an important public health problem among the aging population. Recent studies found that mindfulness-based cognitive therapy (MBCT) can effectively alleviate depressive symptoms in major depressive disorder. The present study explored the clinical effect and potential neuroimaging mechanism of MBCT in the treatment of LLD. We enrolled 60 participants with LLD in an...

DOI: 10.3389/fpsyt.2022.841461 (opens in new tab) Full text (opens in new tab) Amygdala Functional connection Late-life depression Magnetic resonance imaging +2