A network meta-analysis of 68 studies with 5,339 participants compared different mindfulness-based interventions for chronic pain. Mindfulness-based stress reduction showed the strongest evidence for reducing pain intensity and depression, with moderate to high certainty. Mindfulness-oriented recovery enhancement was most effective for improving physical function, though the evidence was low certainty. An 8-week course with weekly 90- to 120-minute sessions appeared optimal for addressing pain, physical function, and depression. These findings support the use of mindfulness-based interventions in chronic pain management and help inform evidence-based guidelines.
Mindfulness-based cognitive therapy (MBCT) is being tested against an active control (Seeking Safety) for people with PTSD symptoms who do not meet full diagnostic criteria. The trial randomly assigns 160 participants to either MBCT or Seeking Safety, each delivered in eight weekly two-hour sessions. PTSD symptoms are measured at baseline, after treatment, and three months later using the PTSD checklist for DSM-5. Secondary outcomes include depression, anxiety, attention, avoidance, rumination, mindfulness, and coping skills. The study also examines whether attention, avoidance, and rumination explain how mindfulness affects PTSD symptoms. Results are expected to inform healthcare guidelines for PTSD.
Loneliness is common among Chinese older adults. A randomized controlled trial compared an 8-week mindfulness-based intervention for older adults (MBOA) with a social contact control (SCC) in 245 community-dwelling lonely adults aged 60 or older in Hong Kong. At 12 months, there was no significant difference in loneliness reduction between the two groups, though both improved (within-group effect size: MBOA -0.58, SCC -0.31). MBOA participants showed reduced depressive symptoms and a trend toward less anxiety at 6 months compared with SCC. The findings suggest MBOA is not superior to social contact for loneliness but may benefit psychological symptoms.