medRxiv
July 10, 2026
Daniel Copeland, Naoise Mac Giollabhui, Louisa G Sylvia et al.
preprint
Background: Despite growing evidence that lifestyle interventions reduce depressive symptoms, the psychological mechanisms underlying these effects remain poorly understood. This study examined whether mindfulness and rumination mediate the antidepressant effects of heated yoga (HY), a multicomponent intervention combining physical activity, attentional training, and thermoregulatory stress....
Aging & Mental Health
June 24, 2025
Paulina Gutierrez-Ramirez, Liliana A. Ramirez Gomez, Miranda Zea et al.
Family dementia caregivers exhibit high rates of chronic psychological stress. We aimed to determine the impact of mentalizing imagery therapy (MIT), a mindfulness and guided imagery approach, on perceived stress and positive psychological traits. We further investigated the role of dispositional mindfulness on these effects. This analysis of secondary outcomes drew from a pilot randomized...
Psychiatric Annals
September 1, 2022
Fernando Espí Forcén, Maren Nyer
To date, ketamine is the only prescribable psychedelic medicine in the United States. Ketamine is also one of the most promising drugs for the treatment of depression. In the current paradigm of care, most ketamine clinics in the United States treat patients with mood disorders with ketamine and its derivatives alone without psychotherapy. The purpose of this article is to review the most...
Psychotherapy and Psychosomatics
March 14, 2022
Felipe A Jain, Sergey V. Chernyak, Lisa D Nickerson et al.
Introduction: Family caregivers of patients with dementia suffer a high burden of depression and reduced positive emotions. Mentalizing imagery therapy (MIT) provides mindfulness and guided imagery skills training to improve balanced mentalizing and emotion regulation. Objective: Our aims were to test the hypotheses that MIT for family caregivers would reduce depression symptoms and improve...
Contemporary Clinical Trials
March 1, 2022
Felipe A Jain, O. Okereke, Laura N. Gitlin et al.
More than 50 million people worldwide live with a dementia, and most are cared for by family members. Family caregivers often experience chronic stress and insomnia, resulting in decreased mental and physical health. Accessibility of in-person stress reduction therapy is limited due to caregiver time constraints and distance from therapy sites. Mentalizing imagery therapy (MIT) provides...
The Journal of Clinical Psychiatry
June 2016
Dawn F. Ionescu, Michaela B Swee, Kara J. Pavone et al.
Ketamine rapidly reduces thoughts of suicide in patients with treatment-resistant depression who are at low risk for suicide. However, the extent to which ketamine reduces thoughts of suicide in depressed patients with current suicidal ideation remains unknown. Between April 2012 and October 2013, 14 outpatients with DSM-IV-diagnosed major depressive disorder were recruited for the presence of...