Aditi Das

2 papers in the library · publishing 2022-2023

Papers

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Experience with dronabinol consumption facilitated a stimulant effect of alcohol and affected alcohol-related changes in frontal cortical endocannabinoid levels in male rats.

Behavioural Brain Research August 24, 2023 Daniel T Sangiamo, Michael J Weingarten, Nnamdi G Nelson et al.

Combined use of cannabis and alcohol is common in adolescents. However, the extent to which such polydrug exposure affects the brain and behaviors remains under-investigated in preclinical studies. This study tested the hypothesis that combined exposure of Δ-9-tetrahydrocannabinol (THC), the main psychoactive constituent of cannabis, and alcohol will have additive effects on cognitive...

DOI: 10.1016/j.bbr.2023.114587 Full text Adolescence Alcohol Barnes maze Endocannabinoids +2

Comparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male and Female Rats.

Cannabis and Cannabinoid Research December 2022 Alexa Torrens, Pritam Roy, Lin Lin et al.

Introduction: Studies in rodent models have shown that adolescent exposure to Δ9-THC, the psychotropic constituent of cannabis, produces long-lasting alterations in brain function and behavior. However, our understanding of how age and sex might influence the distribution and metabolism of THC in laboratory rodents is still incomplete. In the present report, we provide a comparative analysis of...

DOI: 10.1089/can.2021.0205 Full text Cannabis Pharmacokinetics Δ9-tetrahydrocannabinol