Nu-Chu Liang

2 papers in the library · publishing 2023-2024

Papers

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Effects of combined exposure to ethanol and delta-9-tetrahydrocannabinol during adolescence on synaptic plasticity in the prefrontal cortex of Long Evans rats.

Neuropharmacology January 1, 2024 Linyuan Shi, Shuo Kang, Chan Young Choi et al.

Significant exposure to alcohol or cannabis during adolescence can induce lasting disruptions of neuronal signaling in brain regions that are later to mature, such as the medial prefrontal cortex (mPFC). Considerably less is known about the effects of alcohol and cannabis co-use, despite its common occurrence. Here, we used male and female Long-Evans rats to investigate the effects of...

DOI: 10.1016/j.neuropharm.2023.109765 Full text Adolescence Delta-9-tetrahydrocannabinol Ethanol Gaba +3

Experience with dronabinol consumption facilitated a stimulant effect of alcohol and affected alcohol-related changes in frontal cortical endocannabinoid levels in male rats.

Behavioural Brain Research August 24, 2023 Daniel T Sangiamo, Michael J Weingarten, Nnamdi G Nelson et al.

Combined use of cannabis and alcohol is common in adolescents. However, the extent to which such polydrug exposure affects the brain and behaviors remains under-investigated in preclinical studies. This study tested the hypothesis that combined exposure of Δ-9-tetrahydrocannabinol (THC), the main psychoactive constituent of cannabis, and alcohol will have additive effects on cognitive...

DOI: 10.1016/j.bbr.2023.114587 Full text Adolescence Alcohol Barnes maze Endocannabinoids +2