M Darracq

Propofol-induced unresponsiveness is associated with impaired feedforward connectivity in cortical hierarchy.

British Journal of Anaesthesia August 21, 2018 Robert D. Sanders, M I Banks, M Darracq et al.

Background: Impaired consciousness has been associated with impaired cortical signal propagation after transcranial magnetic stimulation (TMS). We hypothesised that the reduced current propagation under propofol-induced unresponsiveness is associated with changes in both feedforward and feedback connectivity across the cortical hierarchy. Methods: Eight subjects underwent left occipital TMS...