Propofol-induced unresponsiveness is associated with impaired feedforward connectivity in cortical hierarchy.
British Journal of Anaesthesia August 21, 2018 Robert D. Sanders, M I Banks, M Darracq et al.
Background: Impaired consciousness has been associated with impaired cortical signal propagation after transcranial magnetic stimulation (TMS). We hypothesised that the reduced current propagation under propofol-induced unresponsiveness is associated with changes in both feedforward and feedback connectivity across the cortical hierarchy. Methods: Eight subjects underwent left occipital TMS...
DOI: 10.1016/j.bja.2018.07.006 (opens in new tab)
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Cerebral cortex
Frontal lobe
Parietal lobe
Humans
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