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Masanori Isobe

3 papers in the library · publishing 2023-2024

Papers

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Associations of conservatism and jumping to conclusions biases with aberrant salience and default mode network

Psychiatry and Clinical Neurosciences February 27, 2024 Jun Miyata, Akihiko Sasamoto, Takahiro Ezaki et al.

While conservatism bias refers to the human need for more evidence for decision‐making than rational thinking expects, the jumping to conclusions (JTC) bias refers to the need for less evidence among individuals with schizophrenia/delusion compared to healthy people. Although the hippocampus‐midbrain‐striatal aberrant salience system and the salience, default mode (DMN), and frontoparietal...

Neural correlates of a mindfulness-based intervention in anorexia nervosa.

BJPsych Open February 2, 2023 Tomomi Noda, Masanori Isobe, Ryo Mishima et al.

We examined the neural underpinnings of the effects of mindfulness on anxiety in anorexia nervosa using functional magnetic resonance imaging in 21 anorexia patients. We used a functional magnetic resonance imaging task designed to induce weight-related anxiety and asked participants to regulate their anxiety either using or not using an acceptance strategy. Our results showed reduced activity...

Associations of conservatism/jumping to conclusions biases with aberrant salience and default mode network

Jun Miyata, Akihiko Sasamoto, Takahiro Ezaki et al. preprint

Abstract: Background and hypothesis: While the conservatism bias refers to the human need for more evidence for decision-making than rational thinking expects, people with schizophrenia and delusion require less evidence, known as the jumping to conclusions (JTC) bias. The midbrain-striatal aberrant salience of schizophrenia is postulated to form delusion; however, the association between...