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Associations of conservatism and jumping to conclusions biases with aberrant salience and default mode network

J. Miyata, A. Sasamoto, T. Ezaki, M. Isobe, Takanori Kochiyama, Naoki Masuda, Y. Mori, Y. Sakai, N. Sawamoto, S. Tei, S. Ubukata, Toshihiko Aso, Toshiya Murai, Hidehiko Takahashi

Psychiatry and Clinical Neurosciences February 27, 2024 DOI: 10.1111/pcn.13652 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Peer reviewed
Topics Default mode network

Abstract

While conservatism bias refers to the human need for more evidence for decision‐making than rational thinking expects, the jumping to conclusions (JTC) bias refers to the need for less evidence among individuals with schizophrenia/delusion compared to healthy people. Although the hippocampus‐midbrain‐striatal aberrant salience system and the salience, default mode (DMN), and frontoparietal networks (“triple networks”) are implicated in delusion/schizophrenia pathophysiology, the associations between conservatism/JTC and these systems/networks are unclear.