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Xiaoyan Wei

2 papers in the library · 3 citations · publishing 2024-2026

Papers

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Single-dose psilocybin promotes cell-type-specific changes of neurons in the orbitofrontal cortex

Neurotherapeutics 2026 Ziran Huang, Xiaoyan Wei, Yihui Wang et al.

Recent clinical breakthroughs hold great promise for the application of psilocybin in the treatments of psychological disorders, such as depression, addiction, and obsessive-compulsive disorder. Psilocybin is a psychedelic whose metabolite, psilocin, is a 5-HT2A receptor agonist. Nevertheless, the underlying mechanisms for the effects of psilocybin on the brain are not fully illustrated, and...

Psilocybin Promotes Cell-Type-Specific Changes in the Orbitofrontal Cortex Revealed by Single-Nucleus RNA-seq

bioRxiv (Cold Spring Harbor Laboratory) January 7, 2024 Ziran Huang, Xiaoyan Wei, Xiaobin Wang et al. 3 citations preprint

Abstract Recent clinical breakthroughs hold great promise for the application of psilocybin in the treatments of psychological disorders, such as depression, addiction, and obsessive-compulsive disorder. Psilocybin is a psychedelic whose metabolite, psilocin, is a 5-HT 2A receptor agonist. Nevertheless, the underlying mechanisms for the effects of psilocybin on the brain are not fully...