A pilot human study using ketamine to treat disorders of consciousness.
iScience January 17, 2025 Paolo Cardone, Arthur Bonhomme, Vincent Bonhomme et al. 9 citations
Post-comatose disorders of consciousness (DoC) represent persistent neurological conditions with limited therapeutic options and a poor prognosis. Recent works advocate for exploring the effects of psychedelics to enhance brain complexity in DoC and ameliorate their consciousness. We investigated sub-anesthetic concentration of the atypical psychedelic ketamine for treating post-comatose...