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Nicolas Lejeune

3 papers in the library · 30 citations · publishing 2025

Papers

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Near‐Death Experience During Emergency Ketamine Use: A Case Report

Brain and Behavior October 1, 2025 Pauline Fritz, Anaïs Pichelin, Aurore Ancion et al. 2 citations

This case, set within its medical and pharmacological context, provides a unique opportunity to study NDEs and their precipitating context. The reported transformations underscore the importance of recognizing NDEs for their possible long-term effects on patients and relevance to medical practice.

A neuroscientific model of near-death experiences.

Nature reviews. Neurology June 1, 2025 Charlotte Martial, Pauline Fritz, Olivia Gosseries et al. 19 citations

Near-death experiences (NDEs) are episodes of disconnected consciousness that typically occur in situations that involve an actual or potential physical threat or are perceived as such, and the experiences are characterized by a rich content with prototypical mystical features. Several explanatory theories for NDEs have been proposed, ranging from psychological or neurophysiological to...

A pilot human study using ketamine to treat disorders of consciousness.

iScience January 17, 2025 Paolo Cardone, Arthur Bonhomme, Vincent Bonhomme et al. 9 citations

Post-comatose disorders of consciousness (DoC) represent persistent neurological conditions with limited therapeutic options and a poor prognosis. Recent works advocate for exploring the effects of psychedelics to enhance brain complexity in DoC and ameliorate their consciousness. We investigated sub-anesthetic concentration of the atypical psychedelic ketamine for treating post-comatose...