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Catherine Walsh

2 papers in the library · 77 citations · publishing 2019-2021

Papers

Mindfulness training and systemic low-grade inflammation in stressed community adults: Evidence from two randomized controlled trials

PLoS One July 11, 2019 Daniella K. Villalba, Emily K. Lindsay, Anna L. Marsland et al. 59 citations

Two randomized controlled trials tested whether mindfulness training reduces inflammation, measured by C-Reactive Protein (CRP), in stressed community adults. One trial used a 2-week smartphone-based intervention; the other used an 8-week Mindfulness-Based Stress Reduction program. Training that combined attention monitoring with acceptance skills did not lower CRP compared to training without acceptance or to a control condition. Exploratory analyses combining data from both studies suggested that either mindfulness approach might reduce CRP in midlife-to-older adults and individuals with high body mass index, populations at risk for systemic inflammation.

Mindfulness-Based Stress Reduction Buffers Glucocorticoid Resistance Among Older Adults: A Randomized Controlled Trial

Psychosomatic Medicine March 3, 2021 Emily K. Lindsay, J. David Creswell, Harrison J. Stern et al. 18 citations

An 8-week Mindfulness-Based Stress Reduction (MBSR) program buffered increases in glucocorticoid resistance (GCR)—a measure of immune cells' reduced sensitivity to anti-inflammatory signals—among lonely older adults aged 65–85, compared with a matched health enhancement program. GCR increased in the control group from before to after the intervention, while the MBSR group showed a small, nonsignificant reduction. The between-group difference was moderate immediately after the program but was not maintained at a 3-month follow-up. The findings suggest MBSR may protect against short-term declines in immune regulation in at-risk older adults.