Mental representations enable the brain to transcend the immediacy of sensory input and operate on internal models of the world. Working memory (WM) provides the neural substrate that maintains, manipulates, and accesses these representations over behaviorally relevant timescales. Early studies identified persistent neuronal activity in the dorsolateral prefrontal cortex as a key mechanism...
EpilepsiaSeptember 2024Derek J Doss, Graham W Johnson, Ghassan S Makhoul et al.
Epilepsy is a common neurological disorder affecting 1% of the global population. Loss of consciousness in focal impaired awareness seizures (FIASs) and focal-to-bilateral tonic-clonic seizures (FBTCSs) can be devastating, but the mechanisms are not well understood. Although ictal activity and interictal connectivity changes have been noted, the network states of focal aware seizures (FASs),...
SUMMARY The human default mode network (DMN) is engaged at rest and in cognitive states such as self-directed thoughts. Interconnected homologous cortical areas in primates constitute a network considered as the equivalent. Here, based on a cross-species comparison of the DMN between humans and non-hominoid primates (macaques, marmosets, and mouse lemurs), we report major dissimilarities in...