Neuropsychopharmacology
July 21, 2026
Alannah Miranda, Breanna M Holloway, Elizabeth Peek et al.
Cannabis use is highly prevalent among people with bipolar disorder, potentially due to a desire to self-medicate against symptoms, such as racing thoughts and poor concentration. Such symptoms are associated with attention and inhibitory control deficits, functions that are regulated in-part by temporal perception. Temporal perception is impaired in BD and is slowed by acute cannabis exposure....
Journal of Cannabis Research
January 2, 2026
Sunitha Vemuri, Samantha M. Ayoub, Arpi Minassian et al.
Cannabinoids have proven to useful for attenuating adverse effects of HIV. People living with HIV use cannabis at higher rates, with evidence suggesting it alleviates physiological symptoms such as nausea, loss of appetite, etc.. Cannabis can alter physiology as well as essential behavioral functions such as motivation. This study investigated the effect of delta-9-tetrahydrocannabinol (THC),...
Brain, Behavior, and Immunity
April 1, 2025
Samantha M. Ayoub, Sunitha Vemuri, Elizabeth B. Hoang et al.
HIV-associated neurocognitive impairment (NCI) is an untreated concern among people living with HIV (PLWH). Cannabis use in PLWH may complicate outcomes on cognition, with evidence to suggest function-dependent effects that are modulated by several factors including use patterns (e.g., frequency of use) and demographic influences (e.g., age). Animal studies can control for these factors. Here,...
Behavioral Sleep Medicine
March 3, 2024
Alannah Miranda, Elizabeth Peek, Sonia Ancoli-Israel et al.
Both sleep and cognition are partially modulated by the endocannabinoid (ECB) system. Cannabis has been reported to have effects on sleep and cognition. This review aims to summarize the recent literature on the ECB system, the role of cannabis and the ECB system on sleep regulation and cognition. Further, this review will identify existing gaps in knowledge and suggest potential targets for...
The International Journal of Neuropsychopharmacology
November 12, 2021
Benjamin Z Roberts, Arpi Minassian, Adam L. Halberstadt et al.
HIV-associated neurocognitive disorder (HAND) is commonly observed in persons living with HIV (PWH) and is characterized by cognitive deficits implicating disruptions of fronto-striatal neurocircuitry. Such circuitry is also susceptible to alteration by cannabis and other drugs of abuse. PWH use cannabis at much higher rates than the general population, thus prioritizing the characterization of...
medRxiv
April 29, 2020
T. Jordan Walter, Nina Pocuca, Jared W Young et al.
1 citation
preprint
ABSTRACT Bipolar disorder (BD) and cannabis use are highly comorbid and are each associated with cognitive impairment. It is therefore important to understand the relationship between cannabis use and cognition in people with BD, as cannabis use in BD may be associated with greater cognitive impairment. We performed a scoping review to determine how much and what is currently known in this...
Journal of Addiction Medicine
March 2011
Rebecca D Crean, Susan F Tapert, Arpi Minassian et al.
This case describes the clinical course of a cannabis-dependent individual entering a 12-week abstinence-based research program. The case illustrates the effects of chronic, heavy cannabis use on executive functions at three time points: 1) 24 hours of abstinence; 2) 4 weeks of abstinence; and 3) 12 weeks of abstinence. It is followed by discussions by two clinical psychologists and a...